Cholesterol; Insulin Levels; Cardiac Disease; 050315


My wife recently had a stent put in. She is otherwise a very healthy person with no blood pressure issues. She just had a couple of kinks in a vein and an artery and they clogged up. Her Triglyceride and cholesterol levels are normal. The medicine she is taking bothers us both. One of which is metaprolol.


Normal is a “relative thing.” This distinction is important, because you want to figure out why people develop certain problems. If they are otherwise healthy, these disorders just don’t happen. If she has a triglyceride level that is over 80, which is normal, but if it is over 80, and borderline high, but still within normal ranges, you will start seeing cholesterol deposits and cardiac issues. A normal cholesterol may not be quite so normal, depending upon what is called “The particle size.”

I would have to ask one thing—what is her CRP? Also, What is her insulin level? If her insulin level is high, you can see this with otherwise normal cholesterol and triglyceride levels. If this is the case, you do things to bring the insulin down.

If her doctors started her on Crestor, it will bring triglycerides down. It does not do anything with regards to the insulin.

1. I would start her on high dose folic acid. Why? It is inexpensive and it brings cholesterol down, and without any physiological collateral damage. Crestor has all manners of problems attached to it, mostly muscular, but it can be nerve-related as well. Folic acid does not, and at dosages over 5,000 mcg, it will lower cholesterol and lower triglycerides.

2. What else can you do to lower the triglycerides instead of using Crestor? You can use Berberine. Berberine will lower triglycerides and lower insulin levels.

These are the things you need to look at, but you have to get the insulin CRP levels drawn first. You have to know where you are starting at.

3. What else can you do? Fish oil. It should be of high quality, not the low quality oil that most people pick up. What I mean by quality, is that it contains the appropriate amount of EPA, which stands for Eicosapentaenoic acid. It is an endothelial anti-inflammatory, and it helps with regard to deposition of cholesterol.

4. What else can you take?. Glucosamine sulfate will help lower CRP, but you should know what the numbers are to get started on it.

About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.