Cucumin is a
spice extracted from turmeric root. This
commonly available spice may be a key to
reduces number of lung metastases and makes the chemotherapy agent, Taxol, less
Taxol, as is true with many chemotherapeutic agents,
provokes an inflammatory response, which
leads to drug resistance. When administered with the chemotherapy, curcumin
inhibited Taxol’s inflammatory response by blocking nuclear factor-kappa B
(NF-kappa B) which regulates inflammation, cell proliferation, and apoptosis
2. Curcumin shuts down the production of NF-Kappa B,
It was determined that curcumin
suppresses tumor necrosis factor (TNF),
from activating NF-kappa B. By inhibiting TNF-induced NF-kappa B
activation, curcumin reduced the expression of genes that regulate every stage
of cancer development.
3. Curcumin inhibits cancer cell growth
NF-kappa B, genes involved in cell proliferation, such as COX-2, cyclin D1, and
c-myc, are inhibited. This means that curcumin suppresses production of
proteins needed for uncontrolled growth and proliferation, inflammation and
inhibition of PGE-
4. Curcumin restores normal control of Apoptosis (Cell Death)
be a condition that damages he normal control mechanism involved in normal cell
death. Curcumin helps to restore normal programmed cell death. The chemotherapy
agent Taxol induced NF-kappa B activation, which leads to cell immortality,
reducing the drug’s ability to kill cancer cells. In that drug resistance is a huge problem, curcumin
can help to make chemotherapeutic agents more effective.
5. Curcumin assists in controlling cancer cell
By inactivating NF-kappa B,
genes promoting metastasis, curcumin inhibits
has been demonstrated to be useful in the treatment and prevention of
acts at the gene-activating level, and is involved in pathways that are
common in inflammatory conditions.
NOTES TO MY PATIENTS:
is useful not only for breast
cancer issues, but for prostate cancer, pancreatitis, and arthritis.
am preparing a newsletter looking at the use of Curcumin as it may pertain
to prevention of heart disease.
may reduce elevated CRP levels, something of intense interest to patients
with heart disease, cholesterol and stroke concerns.
of Curcumin depends upon the strength and purity of the curcumin
top of the line curcumin costs pennies more than the garbage that is
generally available at the ‘health store.’ Using curcumin for the purposes
above requires ‘solvent-free’ curcumin, and I am aware of only one
I am recommending Curcumin (Vital Nutrients, Inc.) 500 mg twice
daily. Cost per month is around $24. The cheaper brands cost a bit less, but
you get a lot less.
can get it from our website, if you wish.