Diabetes Nutraceutical Protocol


Diabetes is a disorder that can be caused from inadequate insulin production, antibodies to insulin and, most commonly, resistance to insulin hormone at the insulin receptor. Known as ‘insulin resistance,’ this type of diabetes is best treated after identification of the underlying cause of the insulin resistance.

The incidence of diabetes is increasing in the general population. Traditional treatment has consisted of oral hypoglycemic agents, which are ‘ molecules new to nature.’ While the use of these agents such as Metformin and Glyburide, may bring down blood sugar, they are not without untoward and undesirable side-effects.

The insulin resistance may be due to nutritional deficiencies in what are known as ‘trace minerals,’ and elevated blood sugars can be successfully treated by systematic and thoughtful replacement of these trace minerals.

The most common mineral deficiencies include zinc, magnesium, and manganese, but the mineral deficiencies that cause diabetes include chromium and vanadium, as well.


Insulin resistance can be defined as an increase in the ratio of serum glucose to serum insulin. This ratio of glucose:insulin (G/I) should be no less than 10:1. Ideal insulin levels, therefore, should never exceed 10, as fasting serum glucose should not exceed ’99.’Ideal insulin level is less than 5, with G/I ratio of 20:1.


Issues regarding glucose dysmetabolism can begin in childhood, but symptoms are most commonly encountered during middle age, many years after the start of this particular disease process. The most common presentation of symptoms are refractory weight gain, dyspepsia, and moderate elevations of blood sugar

Dysfunction of the insulin receptor results in glucose dysmetabolism and abdominal weight gain.

Testing Procedure:

Prior to initiating intervention, it is generally appropriate to establish baseline levels to determine the nature and severity of suspected imbalance. Due to the similarity of symptoms between insulin resistance and hypothyroidism, thyroid issues should be assessed simultaneously with insulin and glucose.

1. Laboratory testing and analysis should be done between 7am and 8am.
2. Laboratory values will include serum (blood) determination of:
a. Fasting blood sugar.
b. Insulin
c. TSH
d. T-3, T-4
e. Anti-Thyroglobulins
f. Thyroid Peroxidase Antibody

3. Blood will be processed as specified by the contracted laboratory, and delivered to the laboratory quickly to minimize degradation due to temperature.

4. Results will be received by dedicated printer from the laboratory.
5. To the extent possible follow-up testing must be performed at the same time and by the same laboratory contractor, thereby improving the ability to compare values over time.

About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.