Enlightened approach to diabetic neuropathy

New Diabetic Neuropathy Treatment Options

There has been a good bit of advertisement for a number of ‘new products’ for the treatment of diabetic neruopathy. Some of these products are very impressive, some, well, not so much.

I have been having some pretty good results using a combination of nutritional intervention with a recently introduced anti-convulsant “Lyrica.”

The trick to using Lyrica is using it principally at bed time, using a dosage sufficient to introduce deep sleep.  Generally, if the patient awakens feeling a little groggy, the dosage is close to being enough.  Introducing a good night’s rest is important for general health, but in the treatment of diabetic neuropathy it is a major blessing. Starting dosage is 50-75 mg at bed time, although the higher dosage seems to work better.  Increase to 150 mg and then 225 mg on 2-3 week intervals.

In addition to the Lyrica, and equally important, is the use of alpha lipoic acid (ALA).  The dosage to introduce is 250 mg three times daily.   After a few weeks, the dosage can be doubled, if the symptoms have not gotten significantly better (which they usually do.)

The combination is quite effective, about 80% of the time.


About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.