Neuropathy & Treatment; 050315


I have been diagnosed with neuropathy and I am taking Venlafaxine 75 ms 3 times a day for neuropathic. But Venlafaxine is used for mood disorders. Why am I taking this medication?


It is called an “Anti-Depressant,” and it is an SNRI, or selective serotonin norepinephrine re-uptake inhibitor. Is it really good for neuropathy? No, it is much better as an anti-depressant, and there are better things to take for neuropathy, if in fact it is neuropathy.

Lyrica is dos an interesting medication, and one of few medications that is truly effective for diabetic neuropathy.

The starting dosage in my practice is 50 milligrams of Lyrica at bedtime. Then, we typically bump it to 75 milligrams at bedtime. What else can you add to the lyrics to make it work a little better?

What is often helpful is the addition of Baclofen. It is also a wonderful anti-convulsant, but it works in conjunction with the calcium channel blockers, and the GABA acting agents.

The Venlafaxine is hard to get on, harder to get off, and I tell you what, it would not be the place I would start. Then, if you want to go naturally, which is not a bad thing, you can start with something called Alpha Lipoid Acid, 1,500 to 2,000 mg once daily, along with GABA 500 mg three times daily.

About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.