Vitamin D-3 in the Prevention & Treatment of Viral Infections and Influenza

Supplemental cholecalciferol (vitamin D) significantly

reduces all-cause mortality emphasizes the medical, ethical, and legal
implications of promptly diagnosing and adequately treating vitamin D
deficiency. Vitamin D deficiency is common, and is implicated in most of the diseases of

Vitamin D-3 is a steroidal hormone that targets
more than 200 human genes in a wide variety of tissues. With genes
asits target, vitamin D has been shown to up-regulate the gene that is
in volved in the production of cathelicidin, a naturally
occurring broad-spectrum antibiotic

of vitamin D deficiency, in otherwise healthy persons involves dosages
between 2,000-7,000 IU vitamin D-3, daily.  With serious systemic
illnesses, associated with vitamin D deficiency, such as cancer,
heart disease, multiple sclerosis, diabetes, autism, the doses should
be somewhat higher to maintain 25(OH)D levels between 55 -70 ng per mL.

Vitamin D-deficient patients
with serious illness should not only be supplemented more aggressively
than the well, they should have more frequent monitoring of serum
25(OH)D and serum calcium.

Doses of vitamin D-3 (2,000 IU
per kg per day for three days) may produce enough of the naturally
occurring antibiotic cathelicidin to cure common viral respiratory
infections, such as influenza and the common cold, but such a theory
awaits further science. This is a very high dosage regimen.  For
general use, Vitamin D-3 dosages of 2,000 to 5,000 IU are sufficient to
enhance immune function and minimize flu symptoms, if exposed to the

D-3 is very inexpensive, about $4 per month.  Because Vitamin D-3 is
oil-soluble, it must be taken with an oil capsule, of almost any type.

David S. Klein, MD, FACA, FACPM is the Medical Director of
the Pain Center of Orlando, Inc.  A graduate
of the University of Maryland School of Medicine, Dr. Klein received training
in General Surgery at the University of North Carolina, and Anesthesiology
at Duke University

 Dr. Klein has been in private practice for 25 years and is
a well published author, lecturing regionally and nationally on topics ranging
from nutritional intervention, hormone replacement and pain treatment.


About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.