Weight Gain, Insulin Resistance and Metabolic Syndrome “X”

Insulin Resistance Syndrome (IRS), sometimes referred to as Metabolic
Syndrome “X” is a medical condition affecting as many as one in four
Americans. Considered to be a ‘pre-diabetic’ state, IRS precedes the
development of diabetes by as much as 10 years.


Insulin is a hormone, secreted by the pancreas. Insulin has two
principal functions: (1) control of blood sugar, and (2) deposition of
free fatty acids into the fat cells. If the insulin receptor becomes
dysfunctional, it takes more and more insulin to maintain normal blood
sugars. Unfortunately, the increase in the Insulin level results in fat
deposition, mostly in the abdomen.


As more and more insulin is needed to maintain blood sugar levels, the
fat cells respond to the situation by becoming ‘fatter.’ This in turn
results in even higher insulin levels. Eventually, blood sugar levels
cannot be maintained, even with the very high insulin levels, and
‘diabetes’ is diagnosed. Clearly, the animals were well out of the barn
by the time ‘diabetes’ was finally diagnosed.


The key to diabetes prevention is detecting ‘insulin resistance’ before
things get totally out of control. In order to do this, serum insulin
levels should be determined simultaneously with blood glucose.


NOTE: Healthy blood sugar to insulin ratio should be greater than 10 to 1.

The first step to restore more normal, lower insulin levels is to treat
with a combination of trace minerals. The key here is balance. Chromium
and vanadium are associated with insulin receptor dysfunction, but
these should not be taken without adequate intake of zinc and selenium.
I use a product called “Magic Minerals,” which is a mixture of organic
mineral salts called ‘chelates.’


The mixture is less expensive than buying the individual components, so
my patients seem to be a bit happier with it. For the average adult,
two capsules are taken twice daily. A bottle of 120 will last 4 weeks.
Many patients will experience some weight loss with “Magic Minerals.”
Typically, patients will lose 4-8 pounds over the course of 6 to 8

After 1-2 weeks of mineral use, blood sugar levels can be expected to
drop. When weight loss ends, additional chromium is administered.
Typically chromium 200 mcg, taken twice daily is added to the ‘Magic
Minerals.’ Alpha Lipoic Acid (ALA) 500 mg taken twice daily will
further sensitize the cells to insulin.

“Magic Minerals” is a balanced mineral chelate, and it is a very good value. It is soy, gluten and egg free.

About David S Klein, MD 149 Articles
David S. Klein, MD, FACA, FACPM was born in Washington, DC, and was raised in Chevy Chase, Maryland. He completed his undergraduate education at the University of Maryland with degrees in Chemistry and Psychology. Medical School was completed at the University of Maryland at Baltimore, followed by Internship in General Surgery at the University of North Carolina and Residency in Anesthesiology at the Duke University, Durham, North Carolina. Dr Klein has been practicing medicine since 1983, concentrating in Pain Medicine, Minimally Invasive Medicine and Surgery, and Neuroendocrinology. Earning Board Certification in Anesthesiology, Dr. Klein was elected Fellow in the American College of Anesthesiology, and he was elected Fellow in the American College of Pain Medicine. He is currently an adjunct Associate Professor at the University of Central Florida, School of Medicine. He has focused his private practice on treating patients with hormone imbalance issues, nutritional deficiency related medical problems as well as pain related issues and impairment. With a highly-complex, CLIA licensed laboratory in-house, he has been able to provide rapid-turn around analysis efficiently and cost-effectively. Lecturing extensively nationally as well as internationally, Dr. Klein has authored many articles on topics relating to pain, injury and nutritionally modulated illness. His radio show, “Pain Free Living,” received top ratings during the 6 years it was on the air. Currently practicing in Longwood, Florida, Dr. Klein practices entirely in the office setting.